Victor Oladipo scored the go-ahead basket with 36 seconds left Saturday, and Jordan Hulls scored 17 points to lead No. 13 Indiana past second-ranked Ohio State 74-70.
Indiana (13-1, 1-1 Big Ten) is the ninth team to defeat a No. 1 ranked team and the No. 2 team in the same season since 1996-97. The Hoosiers are the third team to beat both teams in the same month, having beaten then-No. 1 Kentucky on Dec. 10.
Ohio State (13-2, 1-1) had a five-game winning streak snapped. Aaron Craft led the Buckeyes with 16 points and Jared Sullinger had 15.
The teams traded leads throughout the final eight minutes, but it was Oladipo's layup that gave Indiana a 71-70 lead. Hulls then hit 1 of 2 free throws, making it 72-70 and after William Buford missed a go-ahead 3-ponter with 4.5 seconds to go, Christian Watford sealed the win with two free throws.
NO. 3 KENTUCKY 69,
NO. 4 LOUISVILLE 62
Freshman Michael Kidd-Gilchrist had season-highs with 24 points and 19 rebounds to lead Kentucky (13-1) past Louisville (12-2) to extend the nation's longest home winning streak to 44 games.
Fellow freshman Anthony Davis added 18 points, all in the second half, for the Wildcats in a game that at times looked more like a free-throw shooting contest with 52 fouls.
The Cardinals only led at 2-0 but gave UK all it could handle after rallying from a 15-point deficit behind Russ Smith, who had a career-high 30 points.
NO. 9 UCONN 83,
ST. JOHN'S 69
Shabazz Napier had 17 points and nine assists as Connecticut (12-1, 2-0 Big East) beat St. John's in a game coached by assistants for both teams.
Andre Drummond had 16 points and 11 rebounds and Jeremy Lamb added 15 points for UConn, which shot 60 percent from the floor to win its seventh straight game.
UConn coach Jim Calhoun was serving the second of a three-game suspension for NCAA violations, while St. John's coach Steve Lavin continues to recover from prostate cancer surgery.
NO. 11 WISCONSIN 65
Freshman reserve Aaron White scored 16 of his 18 points in the second half and Iowa stunned Wisconsin (12-3, 1-1 Big Ten) to snap the Badgers' six-game winning streak.
Jordan Taylor had 17 points to lead Wisconsin, which had won its past 12 conference home openers at the Kohl Center.
NO. 12 GEORGETOWN 49,
Henry Sims scored five of his 11 points in the final 7 minutes, and Georgetown (12-1, 2-0 Big East) blew a 14-point lead and shot a season-low 30 percent before downing Providence.
The Hoyas won their 10th straight game despite making only eight field goals in the second half. The score was tied at 35 with 8 minutes to play before Georgetown closed with a 14-5 run.
NO. 15 MISS. ST. 66,
UTAH STATE 64
Rodney Hood scored 16 points, Arnett Moultrie added 15 points and Mississippi State (13-2) escaped against Utah State.
Mississippi State needed a defensive stop on its final possession to seal the win, as Utah State's Danny Berger missed a jumper as time expired that would have tied the game.
NO. 16 MICHIGAN ST. 68,
Draymond Green scored 19 points and Keith Appling had eight of his 14 in the last 7 minutes to help Michigan State (13-2, 2-0 Big Ten) to its 13th consecutive victory.
The Spartans are on their longest winning streak since the 1998-99 team won 22 straight. Eleven of the 13 have been by double digits. Michigan State has won its first two Big Ten games for the fifth straight season.
NO. 17 KANSAS 84,
NORTH DAKOTA 58
Thomas Robinson posted career-bests with 30 points and 21 rebounds, helping Kansas (10-3) overcome a sluggish start to beat North Dakota.
North Dakota had no answer for the muscular 6-foot-10 Robinson. With 12 points and 10 rebounds, the junior had socked away his Big 12-leading ninth double-double by halftime. His monster game included two steals and four assists as the Jayhawks won their 55th straight nonconference home game.
NO. 21 CREIGHTON 68,
WICHITA STATE 61
Antoine Young scored 19 points and Creighton (11-2, 1-1 Missouri Valley) rallied in the second half, holding Wichita State to only 22 points after the break.
NO. 24 HARVARD 74,
SAINT JOSEPH'S 69
Kyle Casey scored 7 of his 26 points in the closing 4:25 as Harvard (12-1) completed a comeback from a late 11-point deficit to beat Saint Joseph's.