SAN DIEGO (AP) — Andrew Cashner probably deserved better.
The big right-hander pitched well, but the San Diego Padres were undone by an eventful fifth inning and lost 6-1 to the Arizona Diamondbacks on Wednesday night.
Daniel Hudson returned from two reconstructive elbow operations to pitch in the big leagues for the first time in more than two years, and David Peralta drove in two runs to lead the Diamondbacks.
Cashner allowed four runs, two earned, and five hits in seven innings. He struck out five and walked one.
But sloppy defense in the fifth and a continued lack of run support hurt Cashner (2-7).
The Diamondbacks scored three runs, two of them unearned, in a fifth inning that included two hits, a walk, two fielder's choices, a call at the plate that stood after a 2 1/2-minute review, a botched rundown and a runner called out on interference.
"I thought the fifth was tough," Cashner said. "I thought it could have gone either way at home, but at the end of the day it's out of your control. For me I just focus on making the next pitch, keep getting outs and you never know what can happen."
Arizona starter Josh Collmenter came up with runners on second and third and one out and hit a grounder to rookie second baseman Corey Spangenberg, whose throw to the plate was just late enough to allow Alfredo Marte to score. Padres manager Bud Black challenged, but the call was confirmed.
That put runners on first and third. Ender Inciarte grounded to first baseman Yasmani Grandal, who threw home to catch Didi Gregorius in a rundown. But third baseman Yangervis Solarte appeared to be going for a quick tag and missed the throw from catcher Rene Rivera. The ball rolled into left field for an error, allowing Gregorius to score.
With Inciarte on second, Collmenter on third and the infield in, Chris Owings hit a grounder to shortstop Alexi Amarista, and Inciarte was called out for interference. Peralta then singled to bring in Collmenter.
Hudson became the fourth pitcher to undergo Tommy John surgery in consecutive years and return to the majors. Hudson, who won 16 games for Arizona in 2011, retired the side in the eighth on 13 pitches and was warmly greeted by his teammates when he reached the dugout.
Hudson hadn't pitched since June 26, 2012, when he originally tore his ulnar collateral ligament. He underwent surgery 15 days later, performed by the late Dr. Lewis Yocum. Hudson tore the ligament again during a rehab start with Double-A Mobile on June 4, 2013, and was operated on two weeks later by Dr. James Andrews.
Collmenter (10-7) won his third straight start, holding San Diego to one run and five hits in seven innings. He struck out three and walked two.
Peralta tripled in Owings in the first.
The Padres' righty has received just 22 runs of support in 94 1-3 innings. His average of 2.1 runs of support is the lowest in the majors among pitchers with 75-plus innings. He has allowed two or fewer earned runs in 16 straight starts at Petco Park, extending the franchise record.
BIG LEAGUE DEBUTS
Padres reliever Leonel Campos made his major league debut when he entered with one out in the eighth, retiring both batters he faced. R.J. Alvarez then made his big league debut when he entered to start the ninth. He allowed one run and one hit with two walks in two-thirds of an inning.
Diamondbacks: Doug Brocail, Mike Lincoln and Denny Stark are the other pitchers who had Tommy John surgery in consecutive seasons and returned to the big leagues.
Padres: Black said SS Everth Cabrera's balky hamstring isn't quite ready for him to be sent out on a rehab assignment.
Diamondbacks: Randall Delgado (2-3, 5.85 ERA) will make his first start since April 10 at San Francisco. He's made two relief appearances against San Diego this season.
Padres: Ian Kennedy (10-11, 3.65) faces his old teammates for the third time this year and fifth time since he was traded from Arizona to San Diego last season.